2463 Schedule of therapeutic substances

STATE HORSE RACING COMMISSION

Schedule of Therapeutic Substances

[43 Pa.B. 7612]
[Saturday, December 28, 2013]

 The State Horse Racing Commission (Commission), in accordance with the Race Horse Industry Reform Act (4 P. S. §§ 325.101—325.402), and more specifically 58 Pa. Code § 163.304 (relating to substances of therapeutic value), adopts the schedule of therapeutic medications established by the Racing Medication and Testing Consortium (RMTC) and adopted by the Association of Racing Commissioners International (ARCI).

 Under 58 Pa. Code § 163.304, the Commission may approve and adopt by reference the RMTC/ARCI schedule of therapeutic medications and their respective threshold levels. On July 11, 2013, at its public meeting the Commission formally approved the schedule set forth as follows. This schedule shall take effect on January 1, 2014. The Commission will publish any subsequent amendments or additions to the RMTC/ARCI therapeutic schedule.

 The Commission did not engage in an independent testing evaluation of the administration times or administration dosage for these medications. Individuals using the enumerated therapeutic medications are encouraged to seek the advice of their respective Veterinarians.

RMTC

Controlled Therapeutic Medications

Substance	Restricted Administration Time	Threshold	Route of Administration	Experimental Administration Dosage
Acepromazine	48 hours	HEPS—10 ng/mL of urine	Intravenous	0.05 mg/kg
Betamethasone	7 days	10 pg/mL in plasma or serum	slntra-articular	9 mg total in one articular space
Butorphanol	48 hours	Free butorphanol— 2 ng/mL of plasma, or Total butorphanol— 300 ng/mL of urine.	Intravenous	0.1 mg/kg
Clenbuterol	14 days	140 pg/mL of urine or LOD in plasma	Oral	0.8 mcg/kg
Dantrolene	48 hours	5-OH dantrolene— 0.1 ng/mL of plasma or serum	Oral	500 mg total dose
Detomidine	72 hours	1 ng/mL of carboxy- detomidine in urine; LOD for detomidine in plasma	Sublingual detomidine (Domosedan gel)	40 mcg/kg
Dexamethasone	72 hours	5 pg/mL of plasma or serum	Oral, Intravenous, IM	0.05 mg/kg
Diclofenac	48 hours	5 ng/mL of plasma or serum	Topical	5" ribbon of Surpass every 12 hours to one site
DMSO	48 hours	10 mcg/mL of plasma or serum	Oral or IV
Firocoxib	14 days	20 ng/nriL of plasma or serum	Oral	0.1 mg/kg for 4 days
Flunixin	24 hours	20 ng/mL of plasma or serum	Intravenous	1.1 mg/kg
Furosemide	4 hours	100 ng/mL in blood and urine specific gravity < 1.010	Intravenous	Up to 500 mg total dose
Glycopyrrolate	48 hours	3 pg/mL of plasma or serum	Intravenous	1 mg total dose
Ketoprofen	24 hours	10 ng/mL of plasma or serum	Intravenous	2.2 mg/kg
Lidocaine (interim)	72 hours	20 pg/mL of total 30H-lidocaine in plasma	Subcutaneous— distal limb	200 mg of lidocaine Hydrochloride salt
Mepivacaine	72 hours	30H-mepivacaine—10 ng/mL in urine or mepivacaine at LOD in plasma	Subcutaneous— distal limb	0.07 mg/kg
Methocarbamol	48 hours	1 ng/mL of plasma or serum	IV or Oral	15 mg/kg IV, 5 g oral
Methylprednisolone	7 days	100 pg/mL in plasma or serum	Intra-articular	100 mg total in one articular space *
Omeprazole	24 hours	omeprazole sulfide— 1 ng/mL in urine	Oral	3.9 mg/kg
Phenylbutazone	24 hours	2 mcg/mL of plasma or serum	Intravenous	4 mg/kg
Prednisolone	48 hours	1 ng/mL of plasma or serum	Oral	1 mg/kg
Procaine penicillin	Time of entry	25 ng/mL of plasma	Intra-muscular
Triamcinolone  acetonide	7 days	100 pg/mL of plasma or serum	Intra-muscular	9mg total in one articular space
Xylazine (interim)	48 hours	0.01 ng/mL of plasma	Intravenous

 * Note: At the 100 mg experimental dose, the safe time for administration to meet the 100 pg/mL threshold was 21 days—the 7 day withdrawal time anticipates that protocols vary and a smaller dose may be utilized which may allow plasma concentrations to fall below the threshold more quickly.

WALTER REMMERT, 
Acting Executive Secretary

[Pa.B. Doc. No. 13-2463. Filed for public inspection December 27, 2013, 9:00 a.m.]